A 6-year-old girl underwent ureterocystoneostomy (UCN) because of left flank pain due to delayed onset of ureteral stenosis one and a half years after Carpet endoscopic dextranomer/hyaluronic acid copolymer (Deflux) injection for the treatment of vesicoureteral reflux (VUR).Histopathological examination indicated chronic inflammation with abundant eosinophils characteristic of a reaction to Deflux.Several autoimmune diseases developed during the treatment for ureteral stenosis.
First, 2 weeks prior to the onset of left flank pain, she was diagnosed as having systemic lupus erythematosus.Finally, she died of pulmonary hemorrhage due to thrombotic thrombocytopenic purpura 4 months after UCN.The fatal outcome in this case was suspected to be caused by autoimmune syndrome induced by adjuvants, which Lacrosse - Protective - Rib in this case was the hyaluronic acid polymer injected into the ureteric orifice for the treatment of VUR.